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General Fitness

Myo-Inositol: Unlocking the Potential Benefits for PCOS

February 18, 2024

Hey there! If you're dealing with PCOS (Polycystic Ovary Syndrome), you've probably come across Myo-inositol as a possible solution. 

In this blog post, we'll learn about Myo-inositol and how it can help you manage PCOS symptoms. We'll cover everything from what Myo-inositol is to how it treats PCOS, the best supplements available, how long you can take it, and whether it's a better choice than metformin. 

So, let's get started!

What is Inositol?

Okay, so let's break it down.

Inositol is a type of sugar alcohol that occurs naturally in our bodies and certain foods. Think of it as a vitamin-like substance that plays a vital role in various cellular functions. Regarding PCOS, Myo-inositol is the form we're most interested in. It's been studied extensively and shows promising effects.

How does Myo Inositol treat PCOS?

Now, let's explore how Myo-inositol can effectively treat PCOS. Inositol is a substance found in our bodies, and two types called Myo-inositol (MI) and D-chiro-inositol (DCI) have important roles in insulin-related effects.

Our bodies absorb MI and DCI when we consume foods like fruits, beans, corn, and nuts. MI has a stronger influence on our cells compared to DCI. It acts like insulin inside our cells, helping to regulate blood sugar levels and balance hormone levels, especially androgens (male hormones).

In PCOS, there's a disruption in inositol and glycosylphosphatidylinositol (GPI) metabolism, which contributes to insulin resistance. MI can help improve insulin sensitivity and hormone balance, reducing symptoms like unwanted hair growth and promoting regular menstrual cycles.

For those aiming to conceive, MI can enhance the action of follicle-stimulating hormone (FSH), potentially improving egg quality and increasing the chances of successful ovulation.

The ratio of MI to DCI is important. This ratio decreases significantly in PCOS (0.2:1), but supplementing with MI can help restore the balance. A recommended ratio of 40:1 has shown positive results in restoring menstrual cycles, increasing progesterone and sex hormone-binding globulin (SHBG) levels, and reducing luteinizing hormone (LH), testosterone, and insulin levels.

Furthermore, MI can help address abnormalities in the menstrual cycle that occur in PCOS. It can reduce LH and androgen levels while improving insulin resistance. This leads to more regular menstrual cycles, especially in obese women with PCOS. MI also helps decrease the risk of developing multiple follicles instead of a dominant follicle, which can improve fertility.

Which inositol supplement is best for PCOS?

Now, let's get down to choosing the right inositol supplement for PCOS. It's crucial to go for a reliable, high-quality product. Look for supplements specifically labeled as "Myo-inositol." These are the ones that have been extensively studied for PCOS.

You'll want to opt for supplements from reputable brands or, better yet, chat with a healthcare professional who can provide personalized advice based on your unique needs.

How long can you take Myo inositol for PCOS?

You might be wondering how long you can safely take Myo-inositol for PCOS. The good news is that it's generally considered safe for long-term use. Since Myo-inositol is a natural substance that our bodies tolerate well, you can incorporate it into your daily routine without worry.

However, it's always wise to consult a healthcare provider to determine the most suitable duration and dosage for your situation.

Which is better: Metformin or Myo-inositol?

Now, this is a common question. Is metformin or Myo-inositol the better choice? Let's break it down.

Metformin is a medication often prescribed for PCOS to manage insulin resistance. While both metformin and Myo-inositol have shown effectiveness in treating PCOS, it's important to consider a few factors. Metformin is a pharmaceutical drug that can come with potential side effects. In contrast, Myo-inositol is a natural compound with a generally favorable safety profile.

The decision between metformin and Myo-inositol depends on various factors, such as your preferences, overall health, and specific needs. Many women find Myo-inositol appealing due to its natural origin and potential for fewer side effects. However, discussing this decision with your healthcare provider to determine the most suitable treatment option for you is essential.


So there you have it! Myo-inositol offers exciting potential as a treatment for PCOS. By incorporating it into your PCOS management plan, you can potentially experience positive changes in your symptoms and overall well-being. Remember, you're not alone on this journey; options are available to support your health and well-being.

Now that you've learned about Myo-inositol and its benefits, take charge of your PCOS journey. Explore the potential advantages, have open discussions with your healthcare team, and together, find the best approach to manage your PCOS effectively.

You've got this!