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Can HRT cause Fibroids?

Fibroids & HRT? Explore if hormone therapy is right for you & manage menopause symptoms without worry.
October 19, 2023

Menopause, a natural transition for women, can bring about various physical changes. Hot flashes, night sweats, and vaginal dryness are some common symptoms that can significantly impact your quality of life. Hormone replacement therapy (HRT), also known as menopausal hormonal therapy (MHT), is an option many women consider to manage these symptoms. However, concerns regarding the potential effects of HRT on uterine fibroids can arise.

What are Uterine Fibroids?

Uterine fibroids are noncancerous growths that develop within the muscular walls of the uterus. These growths are often influenced by estrogen, a female sex hormone. While the exact cause of fibroids remains unknown, factors like family history and hormonal imbalances can play a role. Symptoms of fibroids can vary depending on their size and location. Some women may experience no symptoms at all, while others may experience:

  • Heavy or prolonged menstrual bleeding
  • Pelvic pain or pressure
  • Frequent urination
  • Difficulty emptying the bladder
  • Pain during intercourse

HRT and Fibroids: Addressing the Concerns

Estrogen plays a role in the growth of fibroids. However, the type of HRT and its impact on fibroids need to be differentiated:

  • Estrogen-only HRT: This type of HRT is typically prescribed only for women who have undergone a hysterectomy (surgical removal of the uterus). Since the uterus is absent, there's no risk of stimulating the lining or fibroid growth.
  • Combination HRT (estrogen and progesterone): This is the preferred form of HRT for women with an intact uterus. Progesterone helps counteract the effects of estrogen on the uterine lining, reducing the risk of endometrial hyperplasia (thickening of the lining) and potentially mitigating the growth of fibroids.

Making Informed Decisions with Your Doctor

If you are considering HRT and have concerns about fibroids, it is crucial to have an open and honest conversation with your doctor. They can:

  • Review your medical history, including any existing fibroid diagnosis.
  • Discuss the type and dosage of HRT most suitable for your individual needs.
  • Explain the potential benefits and risks of HRT for fibroids.
  • Monitor your symptoms and adjust the HRT regimen as needed.

Remember: Every woman's experience is unique. Consulting a healthcare professional empowers you to make informed decisions regarding HRT and manage your overall well-being during menopause.

Additional Considerations

  • Seeking a Second Opinion: If you have concerns about your doctor's recommendations, feel free to seek a second opinion from another healthcare provider specializing in women's health.
  • Lifestyle Modifications: Maintaining a healthy weight and engaging in regular exercise can positively impact your overall well-being during menopause, potentially reducing the severity of symptoms.


HRT can be a valuable tool in managing menopausal symptoms and improving your quality of life. By understanding the relationship between HRT and fibroids and by having open communication with your doctor, you can make informed choices about your health and well-being during this transitional phase.